DRUG METABOLIZING ENZYMES: CYTOCHROME P450 AND OTHER ENZYMES IN DRUG DISCOVERY AND DEVELOPMENT

Publisher:
T&F INDIA
| Author:
MICHAEL B. FISHER, JAE S. LEE
| Language:
English
| Format:
Hardback
Publisher:
T&F INDIA
Author:
MICHAEL B. FISHER, JAE S. LEE
Language:
English
Format:
Hardback

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ISBN:
SKU 9780824742935 Category Tags ,
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Page Extent:
68

Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P45 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. This text systematizes findings on P45 and similar enzymes – as well as parallel issues shaping the pharmaceutical industry – to promote the next generation of safer, more effective drugs.

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Description

Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P45 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. This text systematizes findings on P45 and similar enzymes – as well as parallel issues shaping the pharmaceutical industry – to promote the next generation of safer, more effective drugs.

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